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Aesthetic Medicine


Nucleofill is a biostimulator for deep skin renewal and bioreconstruction with a three-way mechanism of action.
It is a preparation for deep skin renewal and bio-restructuring. This innovative treatment works on three levels: lifting, antioxidation and hydration.
It is a unique, triple action at the cellular level that gives the effect of a clear and long-lasting rejuvenation.

Nucleofill is a synonym for innovative biotechnology in aesthetic and anti-aging medicine.
It is a scientifically proven method of skin biostimulation, it contains polynucleotides which stimulate the skin to rebuild in a three-way mechanism.
The first course of action is the receptors on fibroblasts in the skin. Thanks to such stimulation, they transform into myofibroblasts. The process of the production of type I collagen and elastin is stimulated, which causes the skin to thicken and lift.

The second mechanism is the "scavenging" of free radicals and antioxidant activity. Polynucrotides bind water and provide long-lasting iso-osmotic hydration to the extracellular matrix. As a result, the skin becomes moisturized and supple.


  • hypoxic skin
  • skin exposed to oxidative stress
  • dehydrated skin
  • stretch marks and scars
  • photoaging
  • loss of firmness
  • wrinkles


  • pregnancy
  • herpes
  • breast-feeding
  • active autoimmune diseases

The course of the procedure

We administer the preparation with very thin needles that leave no traces at the injection site and minimize pain. After approximately 10-20 minutes of the procedure, the patient can see the immediate result.
Then, after surgery, she can return to her normal daily duties. The full effect is visible after approx
2 weeks. Treatments are performed in a series of 4 treatments every 15-30 days.

The lifting effect after the treatment usually lasts up to 18 months and then the preparation will be naturally absorbed.
Depending on the type (density, concentration, amount) of the Nucleofill preparation used, the treatment should be repeated after 6-20 months.
The great advantage of the preparation is that it does not leave any permanent changes in the skin when the effect wears off.
However, it should be remembered that the durability of the preparation depends on the age, skin type, diet, lifestyle as well as excessive use of sunbaths, saunas and solariums.

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